AI drug pipeline tracker

Phase 1

REC-3565 (MALT1 inhibitor)

Recursion (trial sponsor Exscientia AI Ltd, a Recursion subsidiary): company profile

Phase 1 registry

Since , the date of the source that reports this phase.

Summary

REC-3565 is a MALT1 inhibitor from Recursion (trial sponsor Exscientia AI Ltd, a Recursion subsidiary). The source describes it as small molecule. It is being developed for relapsed or refractory B-cell malignancies, including CLL/SLL and Waldenström's macroglobulinemia. ClinicalTrials.gov lists it at Phase 1 (recruiting) under NCT06980116. The AI role named in the source is molecule design. Registry records: NCT06980116, Phase 1, recruiting, updated Aug 13, 2026. About the company, based in United States: Recursion OS pairs automated phenomic and other high-content biology at scale with machine learning, and since the November 2024 Exscientia combination also includes Exscientia's precision chemistry design. First patient dosed. The latest dated source is from Apr 8, 2025.

Built only from the sources listed on this page.

Facts

Company
Recursion (trial sponsor Exscientia AI Ltd, a Recursion subsidiary)
Indication
Relapsed or refractory B-cell malignancies, including CLL/SLL and Waldenström's macroglobulinemia
Therapeutic area
Oncology
Modality
Small molecule
AI role
Molecule design
Phase in the source
Phase 1, as of Apr 8, 2025
Phase source
Registry
Board column
Phase 1

Key readouts in the source

First patient dosed

AI evidence

AI source: Company

“REC-3565 is a mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitor designed using Recursion’s AI-driven multi-parameter optimization approach.”

Source: developer's own page (opens in new tab)

Trial records

Milestone timeline

  1. Source

    Official X post: Phase 1

    First patient dosed

  2. Registry

    NCT06980116 record updated

    Phase 1, Recruiting

  3. Check

    Registry check

    REC-3565 registered as EXS73565 (MALT1, Exscientia/Recursion).

About Recursion Pharmaceuticals

Recursion OS pairs automated phenomic and other high-content biology at scale with machine learning, and since the November 2024 Exscientia combination also includes Exscientia's precision chemistry design.

Source,

Recursion Pharmaceuticals company profile

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