AI drug pipeline tracker

Phase 1

ISM3412

Insilico Medicine: company profile

Phase 1/2 registry

Since , the date of the source that reports this phase.

Summary

ISM3412 is a program from Insilico Medicine. The source describes it as small molecule. It is being developed for locally advanced or metastatic solid tumors (MTAP-deleted). ClinicalTrials.gov lists it at Phase 1/2 (recruiting) under NCT06414460. The AI role named in the source is molecule design. Registry records: NCT06414460, Phase 1/2, recruiting, updated Sep 1, 2026. About the company: Pharma.AI, an end-to-end generative AI platform covering target discovery (PandaOmics), molecule generation (Chemistry42) and clinical prediction, backed by lab automation. First patient dosed per post. The latest dated source is from Jun 27, 2025.

Built only from the sources listed on this page.

Facts

Company
Insilico Medicine
Indication
Locally advanced or metastatic solid tumors (MTAP-deleted)
Therapeutic area
Oncology
Modality
Small molecule
AI role
Molecule design
Phase in the source
Phase 1/2, as of Jun 27, 2025
Phase source
Registry
Board column
Phase 1

Key readouts in the source

First patient dosed per post

AI evidence

AI source: Company

“ISM3412, a potentially best-in-class, AI-empowered MAT2A inhibitor with a novel structure”

Source: developer's own page (opens in new tab)

Trial records

Milestone timeline

  1. Source

    ClinicalTrials.gov record: Phase 1/2

    First patient dosed per post

  2. Registry

    NCT06414460 record updated

    Phase 1/2, Recruiting

  3. Check

    Registry check

    Registry Phase 1/2 vs post Phase 1.

About Insilico Medicine

Pharma.AI, an end-to-end generative AI platform covering target discovery (PandaOmics), molecule generation (Chemistry42) and clinical prediction, backed by lab automation.

Source,

Insilico Medicine company profile

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